潘玉峰 教授,博士生導師
電話:025-83790776
E-mail: pany@seu.edu.cn
Labweb: panylab.org
辦公地點:南京市四牌樓2号,李文正北樓214室
個人簡介:
2004年7月畢業于南開大學生物物理學專業獲得學士學位,2009年7月畢業于中國科學院生物物理研究所神經生物學專業獲得博士學位。自2009年9月起在美國著名的霍華德休斯醫學研究所(Janelia Research Campus, Howard Hughes Medical Institute)做博士後工作。2014年受聘為東南大學生命科學研究院教授,2016年獲得國家優秀青年基金以及江蘇省傑出青年基金。現為beat365体育官网平台教授、博士生導師、副院長。
研究方向:動物行為的遺傳與神經生物學機制
行為是如何産生的?先天獲得的或是後天學習的?先天獲得、後天學習的神經機制是什麼?兩性行為的天然差異是如何産生的?不同行為之間的轉換與選擇(比如睡眠、覓食、求偶)在分子和神經元水平的機制又是什麼?本實驗室以經典模式動物果蠅為模型,運用遺傳學、光遺傳學、行為學、分子生物學、電生理以及功能成像等技術手段研究動物行為的遺傳與神經生物學機制。更多信息,請參見本實驗室主頁: panylab.org
近期代表性論文:
Han, C., Peng, Q., Sun, M., Jiang, X., Su, X., Chen, J., Ma, M., Zhu, H., Ji, X., Pan, Y. (2022) The doublesex gene regulates dimorphic sexual and aggressive behaviors in Drosophila. PNAS,119 (37) e2201513119. https://doi.org/10.1073/pnas.2201513119
Han, C., Peng, Q., Su, X., Xing, L., Ji, X., Pan, Y. (2022) A male-specific doublesex isoform reveals an evolutionary pathway of sexual development via distinct alternative splicing mechanisms. Communications Biology, 5(1): p. 728. https://www.nature.com/articles/s42003-022-03664-7
Jiang, X. and Pan, Y. (2022) Neural Control of Action Selection Among Innate Behaviors. Neuroscience Bulletin, https://doi.org/10.1007/s12264-022-00886-x
Jia, Y., Jin, S., Hu, K., Geng, L., Han, C., Kang, R., Pang, Y., Ling, E., Tan, E., Pan, Y.* and Liu, W.* (2021) Gut microbiome modulates Drosophila aggression through octopamine signaling. Nature Communications,12, 2698. (*Corresponding authors) https://doi.org/10.1038/s41467-021-23041-y
Chen, J., Jin, S., Chen, D., Cao, J., Ji, X., Peng, Q., Pan, Y. (2021) fruitless tunes functional flexibility of courtship circuitry during development.eLife, 10: e59224. https://elifesciences.org/articles/59224
Peng, Q, Chen, J, Pan, Y. (2021) From fruitless to sex: On the generation and diversification of an innate behavior. Genes, Brain and Behavior, e12772. doi:10.1111/gbb.12772. https://onlinelibrary.wiley.com/doi/full/10.1111/gbb.12772
Gao, C., Guo, C., Peng, Q., Cao, J., Shohat-Ophir, G., Liu, D., and Pan, Y. (2020) Sex and Death: Identification of Feedback Neuromodulation Balancing Reproduction and Survival. Neuroscience Bulletin,36, 1429–1440. https://doi.org/10.1007/s12264-020-00604-5
Wu, S., Guo, C., Zhao, H., Sun, M., Chen, J., Han, C., Peng, Q., Qiao, H., Peng, P., Liu, Y., Luo, S. D., and Pan, Y. (2019) Drosulfakinin signaling in fruitless circuitry antagonizes P1 neurons to regulate sexual arousal in Drosophila. Nature Communications,10, 4770. https://doi.org/10.1038/s41467-019-12758-6
Zhang, W., Guo, C., Chen, D., Peng, Q., and Pan, Y. (2018). Hierarchical Control of Drosophila Sleep, Courtship, and Feeding Behaviors by Male-Specific P1 Neurons, Neuroscience Bulletin, 34, 1105–1110. https://doi.org/10.1007/s12264-018-0281-z
Chen, D., Sitaraman, D., Chen, N., Jin, X., Han, C., Chen, J., Sun, M., Baker, B.S., Nitabach, M.N., and Pan, Y. (2017). Genetic and neuronal mechanisms governing the sex-specific interaction between sleep and sexual behaviors in Drosophila. Nature Communications, 8, 154. https://doi.org/10.1038/s41467-017-00087-5
Pan, Y.*, and Baker, B.S.* (2014). Genetic identification and separation of innate and experience-dependent courtship behaviors in Drosophila. Cell, 156, 236-248. (*Corresponding authors) https://doi.org/10.1016/j.cell.2013.11.041
Pan, Y., Meissner, G.W., and Baker, B.S. (2012). Joint control of Drosophila male courtship behavior by motion cues and activation of male-specific P1 neurons. PNAS, 109, 10065-10070. https://doi.org/10.1073/pnas.1207107109