方海同

發布者:系統管理員發布時間:2019-08-23浏覽次數:6196


    方海同     副教授、碩士生導師

    電  話:                    

     Email:: 101012396@seu.edu.cn

    辦公地點:bet356在线官方网站四牌樓校區李文正樓北233



個人簡介:

19989月 — 20027月    學士, 生物化學專業,安徽大學

20059月 — 20086月    碩士, 生物化學與分子生物學專業,中國科學技術大學

20089月 — 20127月    博士, 細胞生物學專業,中國科學院動物研究所

20128月 — 20185月    博士後,新加坡分子與細胞生物學研究所

201811月至今                  副教授, bet356在线官方网站


研究方向:

1.幹細胞命運決定

2. 表觀遺傳學



近期代表性論文:

1. Fang HT, El Farran CA, Xing QR, Li P, Cheng H, Tushar W, Xu J, Zhang LF, Li H, Lim B, Loh YH. (2018) Global H3.3 dynamics defines its bimodal role in cell fate transition. Nature Communications. Apr 18;9:1537

2. Mzoughi S, Zhang JX, Hequet D, Teo SX, FangHT, Xing QR, Bezzi M, Ong SL, Shin ME, Wollmann H, Wong E, Al-Haddawi M, Stewart C, Tergaonkar V, Dunn NR, Loh YH, Messerschmidt DM and Guccione E.(2017) PRDM15 safeguards naïve pluripotency by transcriptionally regulating WNT and MAPK/ERK signaling. Nature Genetics. Sep;49(9):1354-1363.

3. Cheng H, Ang YK, El Farran CA, Li P, Fang HT, Liu Tongming, Kong SL, Chin LZ, Ling WY, Lim KH, Li H, Huber T , Loh M, Loh YH, Lim B.(2016) Reprogramming Mouse Fibroblasts into EngraftableMyeloerythroid and Lymphoid Progenitors: Induction and Underlying Mechanisms. Nature Communications. Nov 21;7:13396.

4. Yang BX*, El Farran CA*, Guo HC*, Yu T*, Fang HT, Wang HF, Schlesinger S, Seah YF, Goh GY, Neo SP, Li Y, Lorincz MC, Tergaonkar V, Lim TM, Chen L, Gunaratne J, Collins JJ, Goff SP, Daley GQ, Li H, Bard FA, Loh YH. (2015) Systematic identification of factors for provirus silencing in embryonic stem cells. Cell. Sep; 163(1): 230-245.

5. Fang HT, Zhang B (Co-author), Pan XF, Gao L, Zhen T, Zhao HX, Ma L, Xie J, Liu Z, Yu XJ, Cheng X, Feng TT, Zhang FX, Yang Y, Hu ZG, Sheng GQ, Chen YL, Chen SJ, Chen Z, Zhou GB.(2012) Bortezomib interferes with C-KIT processing and transforms the t(8;21)-generated fusion proteins into tumor- suppressing fragments in leukemia cells. PNAS. Feb; 109(7): 2521-2526.

6. Zhou GS, Hu Z, Fang HT, Zhang FX, Pan XF, Chen XQ, Hu AM, Xu L, Zhou GB. (2011) Biologic activity of triptolide in t(8;21) acute myeloid leukemia cells. Leukemia Research. Feb; 35(2): 214-218.





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