芮夢龍

       芮夢龍 副研究員、碩士生導師

    電話：

    Email：ruimenglong@seu.edu.cn

    辦公地點：bet356在线官方网站四牌樓校區李文正樓北227室

個人簡介：

2007年10月-2011年6月  學士，生物技術，蘇州科技大學

2011年9月-2017年12月  博士，生物學，bet356在线官方网站

2018年3月-2020年6月   博士後，新加坡淡馬錫生命科學研究院

2021年2月-至今        副研究員，bet356在线官方网站

研究方向：

1.神經發育與疾病；

2.突觸發育與功能。

近期代表性論文：(# co-first author; * corresponding author)：

1. Jianzheng He, Alice Mei Xien Tan, SiYun Ng, Menglong Rui, Fengwei Yu*. Cannabinoids modulate food preference and consumption in Drosophila melanogaster. (2021) Scientific Reports. 2021 Feb 25;11(1):4709. doi: 10.1038/s41598-021-84180-2.

2. Menglong Rui^#, Shufeng Bu^#, Liang Yuh Chew^#, Qiwei Wang, Fengwei Yu*. The membrane protein Raw regulates dendrite pruning via the secretory pathway. (2020) Development. 2020 Oct 9;147(19):dev191155. doi: 10.1242/dev.191155.

3. Quan Tang, Menglong Rui, Shufeng Bu, Yan Wang, Liang Yuh Chew, and Fengwei Yu*. A microtubule polymerase is required for microtubule orientation and dendrite pruning in Drosophila. (2020) The EMBO Journal. 2020 May 18;39(10):e103549. doi: 10.15252/embj.

4. Menglong Rui^#, Kay Siong Ng^#, Quan Tang, Shufeng Bu, Fengwei Yu*. Protein phosphatase PP2A regulates microtubule orientation and dendrite pruning in Drosophila. (2020) EMBO Reports. 2020 Mar18: e48843. doi: 10.15252/embr.

5. Yan Wang^#, Menglong Rui^#, Quan Tang, Shufeng Bu, Fengwei Yu*. Patronin governs minus-end-out orientation of dendritic microtubules to promote dendrite pruning in Drosophila. (2019) Elife. 2019 Mar 28;8. pii: e39964. doi: 10.7554/eLife.39964.

6. Guanglin Xing^#, Moyi Li^#, Yichen Sun, Menglong Rui, Yan Zhuang, Huihui Lv, Junhai Han, Zhengping Jia*, Wei Xie*. Neurexin-Neuroligin 1 regulates synaptic morphology and functions via the WAVE regulatory complex in Drosophila neuromuscular junction. (2018) Elife. 2018 Mar 14;7. pii: e30457. doi: 10.7554.

7. Menglong Rui, Jinjun Qian, Lijuan Liu, Huihui Lv, Junhai Han, Zhengping Jia and Wei Xie*. The neuronal protein Neurexin directly interacts with the Scribble-Pix complex to stimulate F-actin assembly for synaptic vesicle clustering. (2017) Journal of Biological Chemistry. 2017 Sep 1;292(35): 14334-14348.

8. Xinwang Zhang, Menglong Rui, Guangmin Gan, Cong Huang, Jukang Yi, Huihui Lv, Wei Xie*. Neuroligin4 regulates synaptic growth via the bone morphogenetic protein (BMP) signaling pathway at the Drosophila neuromuscular junction. (2017) Journal of Biological Chemistry. 2017 Nov 3;292(44):17991-18005.

9. Renjun Tu, Jinjun Qian, Menglong Rui, Nana Tao, Mingkuan Sun, Yan Zhuang, Huihui Lv, Junhai Han, Moyi Li and Wei Xie*. Proteolytic cleavage is required for functional neuroligin 2 maturation and trafficking in Drosophila. (2017) Journal of Molecular Cell Biology. 2017 Jun 1;9(3): 231-242.

10. Xi Xiao, Changyan Chen, Tian-ming Yu, Jiayao Ou, Menglong Rui, Yuanfen Zhai, Yijing He, Lei Xue, and Margaret S. Ho*. Molecular Chaperone Calnexin Regulates the Function of Drosophila Sodium Channel Paralytic. (2017) Frontiers in Molecular Neuroscience. doi:10.3389/fnmol.2017.00057.